PRP is an abbreviation for Platelet-Rich Plasma. In Japanese, it is called platelet-rich plasma and refers to platelet-rich plasma. When a blood vessel is damaged, 100,000 to 400,000 platelets per 1 mm 3 of blood gather at the damaged place to stop bleeding, and at that time, a large amount of growth factor is released. This growth factor serves to initiate the process of tissue repair.

Overseas, PRP therapy has been used mainly for tissue repair of muscles and ligaments of soccer players, major leaguers and professional golfers since around 2000, in the orthopedic field, elbows and knees due to sports injuries. It is attracting attention for its pain and damage to tendons and muscles. PRP therapy has been attracting attention as a more natural treatment that enhances self-healing power, because existing steroid treatments suppress tissue healing even if pain is relieved. Although there are many reports of clinical use, the views on the results are not fixed and have not yet been established as a treatment method. However, there are reports of clinical results such as minimal invasiveness and early recovery for sports injuries, so it is a regenerative medicine that is expected to develop in the future. Especially recently, it has been in the limelight as a new biotherapy to be administered into the knee joint (a new treatment method that uses components derived from one's own cells and blood to treat diseases and repair damaged tissues).

Generally, tissue repair occurs in 1 week to 6 months, and the effect can be expected to appear in 2 weeks to 3 months after treatment. It is also possible to repeat treatment.Hier Absätze hinzufügen.

-Stimulates platelet-derived growth factor (PDGF-aa, PDGF-ab, PDGF-bb)
cell replication. Promotes angioplasty, epithelial formation, and granulation tissue formation.
-Transforming growth factor (TGF-β1, TGF-β2)
Promotes extracellular matrix formation. It regulates the metabolism of bone cells.
・ Vascular Endothelial Growth Factor (VEGF)
Promotes angioplasty.
-Fibroblast Growth Factor (FGF)
Promotes the proliferation of endothelial cells and fibroblasts. Stimulates angioplasty.

・ Because it is derived from self-tissue, allergies are unlikely to occur.
・ One-day treatment is possible.
・ You can live a normal life after treatment.
・ The treatment procedure is simple and treatment marks are unlikely to remain.
・ You can take it as many times as you like.
・ You can take it at any time of hyperacute, acute, subacute, and chronic.
・ It is possible to treat most of the locomotorium such as muscles, tendons, and ligaments.

・ Because it uses your own blood, it depends on your physical condition and age, and in some cases it may be difficult to obtain a stable effect. (There are individual differences in the therapeutic effect and duration of the effect.)
・ Inflammation (pain, heat, redness, swelling) is accompanied for several days. (Swelling may last for about a week depending on the treatment site.)
・ When a wide range of treatments are performed at one time, hardness and lumps may remain.
・ Subcutaneous bleeding may occur at the blood collection site / treatment site.
・ Infectious diseases may occur at the administration site and blood collection site.
・ Treatment cannot be covered by public medical insurance such as social insurance and national health insurance.

(Treatment flow) Blood sampling with PRP Tubes ⇒ PRP separation with PRP centrifuge ⇒ Treatment
All treatments will be completed within the day. Local anesthesia may be given.
1. Blood collection: Collect approximately 26 to 52 mL of blood per kit.
2. PRP separation: Centrifuge the collected blood to make PRP.
During this time, patients should wait in the waiting room. (About 30 minutes) If
you want an extracorporeal shock wave at the same time, do it during this waiting time.
3. Treatment: Puncture the injured area and inject it. If necessary, use ultrasound to confirm the exact location of the damage

・ Please refrain from stimulating the treatment area such as strenuous exercise, drinking, and massage on the day of treatment.
・ On the day of treatment, do not put the administration site in the bathtub to prevent infection at the treatment site. From the day after the treatment, you can put it in the bathtub.
・ For several days after administration, activities that improve blood flow (long bathing, sauna, exercise, drinking, etc.) may increase the pain associated with treatment. However, there is no difference in the therapeutic effect just because this pain has become stronger.
・ If you experience any discomfort or inconvenience, please contact our clinic during the consultation hours instead of treating yourself or treating at another hospital.
・ If you have any other problems or symptoms that you are worried about, please do not hesitate to contact us. If necessary, we will explain or provide medical support. We will also notify you as soon as we find any new safety information.
・ If any health damage occurs, we will provide appropriate medical care and respond to consultations.hinzufügen.

After injection for one week from the next day , cells are activated and promoted, which may cause redness and pain, but then disappear spontaneously.

We will proceed with rehabilitation according to each disease while checking the progress by medical examination for 1 to 4 weeks .

For　those who wish to return to sports 1 to 2 weeks later, we will perform post-PRP rehabilitation.

After the injection, it takes at least one month to return to sports, depending on the site, because it activates the body's natural healing process and promotes healing and self-renewal . During that time, it is recommended to avoid moving the affected area as much as possible and protect it with a supporter if possible. Supporters can be purchased at PEP OSAKA (training facility) attached to this hospital.

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• In addition to the PRP treatment performed this time, the following injection therapies are currently being performed.
  ・ Treatment with steroids: In expectation of so-called pain-relieving injection
  anti-inflammatory effect, treatment with steroids is usually performed in clinical practice, but on the contrary, serious infections due to side effects of steroids. Induction of steroids, exacerbation of osteoporosis, difficulty in withdrawal of drugs, etc. may occur. In addition, although steroids are effective for the purpose of relieving pain, they also reduce the healing ability to tissues, so administration to athletes is prohibited by the sports medicine society, so a special application is required when administration. is. If it is about once, it will not have a big effect on the body, but the side effects of steroids by hitting it many times are not a little. It is a rare treatment that is rarely done at our hospital.

• ・ Treatment with sodium hyaluronate: So-called hyaluronic acid injection
  is covered by insurance for intra-knee and intra-shoulder joints, and can be administered mainly for knee osteoarthritis and periarthritis of the shoulder over 40 years old. It is accepted. Its effects are anti-inflammatory or machine oil-like, but it does not have the ability to repair tissues. I'm telling patients that just because they hit hyaluronic acid doesn't mean they'll be repaired, so it's not a treatment that can be expected to be overly effective. The concentration of hyaluronic acid originally present in joints decreases as the production capacity declines with age, and older joints require more hyaluronic acid than the hyaluronic acid produced, so hyaluronic acid is relatively high. I'm talking about putting it in a broken joint for the purpose of replenishing it. However, since many people can improve their symptoms just by supplementing them, hyaluronic acid will be the first choice for outpatient injections into the shoulder and knee joints covered by insurance even if PRP therapy is started. However, since it is only approved for insurance coverage for people over 40 years old, it cannot be administered to people under 40 years old.

• PRP therapy has been shown to be as effective as steroids in terms of pain improvement and more effective than hyaluronic acid in terms of healing effects. There are many patients who have been administering hyaluronic acid intra-articularly at our hospital, but even if PRP therapy is available, those who are urgently administering hyaluronic acid need to switch to PRP therapy. there is no. Especially for those who have been taking hyaluronic acid for a long time and their symptoms have subsided, there is no need to change it, and I think it is better to continue taking it. This is because hyaluronic acid is covered by insurance, and although PRP therapy is a state-approved treatment, it still costs a lot of money for medical treatment. Although it is not enough for surgery, hyaluronic acid alone does not improve pain and swelling, and it is difficult to treat, and for patients under 40 years old who want to take hyaluronic acid but are not covered by insurance, next It may be expected as a generational method. In any case, it costs a lot of medical expenses, so please decide carefully. Also, it is not a method that works for everyone. The therapeutic effect depends on the health condition and individual differences. Please note.　

Based on the above, please carefully consider whether or not to receive PRP treatment.

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PRP may not be separated depending on the patient's physical condition or the condition of the collected blood.

In addition, although the equipment that concentrates PRP is regularly maintained, we ask for your understanding as the treatment schedule and time may change due to sudden malfunctions.

If you would like to receive both knees at once, we recommend one at a time. About 60cc of blood is collected at one time, so both are a heavy burden on the body. However, you can receive two places outside the joint, such as the elbow and shoulder, at the same time.